Reading Diary_Useful Phrases

30 Nanobiotechnology, biomedicine terms

Source: [1] Qiang L. et al. A novel macrophage-mediated biomimetic delivery system with NIR-triggered release for prostate cancer therapy. Journal of nanobiotechnology, 17(1) (2019), pp. 1-15. Source: [2] Navolokin N. A. et al. Systemic administration of polyelectrolyte microcapsules: where do they accumulate and when? in vivo and ex vivo study. Nanomaterials, 8(1), p. 812. Source: [3] Pang L. et al. Primary M1 macrophages as multifunctional carrier combined with PLGA nanoparticle delivering anticancer drug for efficient glioma therapy. Drug Delivery, 25(1), pp. 1922-1931.

Along with that
phrase
1 : in addition to (something or someone) a plane carrying heavy radar equipment along with full fuel tanks. 2 : together with (something or someone) A bill came along with the merchandise.
Example: [2] Along with that, AAS allows detection of iron element biodistribution at all stages of capsule accumulation and degradation, including monitoring of iron before and after microcapsule and nanoparticle degradation.
en: Наряду с этим
As depicted in
phrase
represent by a drawing, painting, or other art form.
Example: [3]As depicted in Figure 6(A), DOX@NPs, M1 treatment group all elicited slight extension in life span over DOX and PBS control group, with their median orderly being 26.5 days, 25 days, 21 days, and 21 days, respectively.
en: Как изображено на
based on the above data
phrase
relying on observation or experiment; "experimental results that supported the hypothesis" observational, experimental.
Example: [1] Based on the above data (Fig. 4a), we finally determined that the drug loading method of macrophages was: incubating with the PBS solution of DOX/PEG-BPEI-rGO (DOX 30 μg/mL) for 40 min.
en: на основании приведенных выше данных
compared with
phrase
to examine (two or more objects, ideas, people, etc.) in order to note similarities and differences
Example: [1] Compared with free DOX, DOX/PEG-BPEI-rGO produced a much lower cytotoxicity at high concentrations (Fig. 4b), which provided the basic condition for the macrophages to be loaded with DOX/PEG-BPEI-rGO.
en: по сравнению с
Despite that
phrase
without being affected by; in spite of.
Example: [3] Despite that, the tumor homing capacity still maintained promising tumor tropism capability.
en: Несмотря на это
have attracted much attention
phrase
to make someone notice someone or something
Example: [1] In recent years, biomimetic delivery systems (BDS) using endogenous cells to transport therapeutic agents to the tumor sites have attracted much attention.
en: привлекли много внимания
in accordance with
phrase
in a way that agrees with or follows (something, such as a rule or request)
Example: [2] Animal experiments were performed in accordance with the University’s Animal Ethics Committee.
en: в соответствии с
In order to evaluate
phrase
If you evaluate something or someone, you consider them in order to make a judgment about them, for example about how good or bad they are.
Example: [2] In order to evaluate microcapsules presence in organs, a quantitative magnetite content analysis of ex vivo samples was performed using the ESR method .
en: Чтобы оценить
It should also be noted
phrase
it should also be pointed out that
Example: [2] It should also be noted that in the lungs, a marked allergic reaction was observed during all time intervals, which was manifested by the appearance of perivascular lymphoid infiltration, and further abrupt thickening of the vessel walls, as well as more pronounced hyperplasia of bronchial lymphoid tissue, which was observed one month after the intravenous administration of the capsules.
en: Также следует отметить
it was found in our studies
phrase
it was based on our research
Example: [3] Furthermore, it was found in our studies the phagocytic capability of M0 macrophage was so limited that it is difficult to meet therapy needs, while M1 macrophages as activated macrophage can uptake particles threefold higher than that of M0 macrophages, which can satisfy therapeutic dosage.
en: это было найдено в наших исследованиях
It was hypothesized that
phrase
put (something) forward as a hypothesis.
Example: [3] It was hypothesized that using nanoparticle instead of free drug can overcome these problems.
en: Было высказано предположение, что
It was noteworthy that
phrase
worth paying attention to; interesting or significant.
Example: [3] It was noteworthy that M1-NPs significantly prolonged mice survival with median survival 38.5 days (M1-NPs vs. all other groups, p < .05).
en: Примечательно, что
It was supposed that
phrase
generally assumed or believed to be the case, but not necessarily so.
Example: [3] It was supposed that it will be gradually released by exocytosis in exosome form.
en: Предполагалось, что
it would avoid
phrase
keep away from or stop oneself from doing (something).
Example: [3] On the one hand, it would avoid the efflux effect of P-glycoprotein; on the other hand, it can delay the toxicity of drug to cell carrier by blocking the direct contact between cell carrier and drug.
en: это позволит избежать
knowing that
phrase
done in full awareness or consciousness.
Example: [1] Knowing that the essential requirement of a biomimetic drug delivery system is that the drug-loaded cells can maintain their activity after drug loading we detected cell viability of the macrophages by CCK-8 assay.
en: знаю это
may be due to
phrase
as a result of; because of
Example: [1] Size reduction and thickness increase may be due to the folding and reforming of GO during the connecting and reduction process.
en: может быть из-за
research has been undertaken to illustrate
phrase
a detailed study of a subject, especially in order to discover (new) information or reach a (new) understanding
Example: [2]This research has been undertaken to illustrate the promise of addressed delivery to particular sites in the body with the help of magnetic nanoparticles externally navigated with a magnetic field.
en: было проведено исследование, чтобы проиллюстрировать
research was conducted in
phrase
projects implemented
Example: [1] The tumor targeting ability of the drug-loaded macrophages was investigated in vitro and in vivo, and anti-cancer efficacy research was conducted in a mouse prostate cancer model.
en: исследования проводились в
taking these together
phrase
If you put something together, you join its different parts to each other so that it can be used.
Example: [3] Taking these together, M1-NPs could serve as an efficient and safe formulation for glioma therapy.
en: принимая это вместе
The early attempt was to
phrase
to make an effort to do, accomplish, solve, or effect
Example: [3]The early attempt was to synthesize ligand-modified liposomes, which were captured by neutrophils in circulation after injection; then, the liposomes were indirectly transported into the site of lesion in stroke model
en: Ранняя попытка заключалась в том, чтобы
The major demand in
phrase
very popular
Example: [2] The major demand in the area is how to direct the vesicles to the tumor site, which remains challenging due to side effects.
en: Основной спрос в
These data are consistent with the data from other studies
phrase
always behaving or happening in a similar
Example: [2] These data are consistent with the data from other studies [40,41], in which it was shown that nanoparticles are actively phagocytosed and accumulated in the organs with a large content of tissue macrophages.
en: Эти данные согласуются с данными других исследований.
these results indicated that
phrase
to show, point, or make clear in another way
Example: [1] These results indicated that MAs-DOX/PEG-BPEI-rGO could maintain stability before reaching the tumor site, and release the encapsulated DOX rapidly upon receiving irradiation.
en: эти результаты показали, что
This fact underpins
phrase
1 : the material and construction (such as a foundation) used for support of a structure. 2 : something that serves as a foundation : basis, support —often used in plural the philosophical underpinnings of educational methods.
Example: [2] This fact underpins the possibility of application of the ESR method to the quantitative analysis of magnetite microcapsules in ex vivo samples.
en: Этот факт подкрепляет
This is likely attributed to
phrase
to indicate that something is probably the case or will probably happen in a particular situation
Example: [3] This is likely attributed to the size differences between NPs and M1-NPs. M1-NPs in around 10 µm diameter easily stuck in blood capillary enriched lung.
en: Вероятно, это связано с
this strategy combines
phrase
a carefully developed plan or method for achieving a goal or the skill in developing and undertaking such a plan or method
Example: [1] This strategy combines the natural function of macrophages and the property of rGO. DOX/rGO is transported to the tumor site by means of chemotaxis of the macrophages.
en: эта стратегия сочетает в себе
this study is based on
phrase
according to this study
Example: [2] The modified procedure of ESR spectroscopy in this study is based on the recording of ferromagnetic resonance spectra reflecting the magnetite content in a specimen.
en: это исследование основано на
to enhance the efficacy
phrase
to intensify or increase in quality, value, power, etc
Example: [1] Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents.
en: для повышения эффективности
tumor bearing mice
phrase
mice with tumor
Example: [1] The tumor bearing mice were equally randomized into seven groups.
en: мышей с опухолью
were performed using
phrase
to do an action or piece of work:
Example: [2] The measurements of the zeta-potential and size distribution of nanoparticles were performed using a Zetasizer Nano-ZS instrument.
en: были выполнены с использованием